Gallbladder involvement of diffuse large B-cell lymphoma mimicking gall- bladder carcinoma

We report a case of diffuse large B-cell lymphoma of the gallbladder mimicking gallbladder carcinoma. In this case, ERCP-guided brush cytology was useful for the differential diagnosis. A 54-year-old male was admitted to the hospital due to abdominal pain in September 2009. A physical examination revealed cervical lymphadenopathy. The laboratory data revealed increased serum levels of LDH (539 IU/l) and soluble interleukin-2 receptor (1230 U/ml). Abdominal ultrasonography (US) showed gallbladder wall thickening. Contrast computed tomog- raphy (CT) revealed irregular thickening of the gallblad- der wall. The gallbladder lesion showed low-intensity on T1-weighted magnetic resonance (MR) images and high intensity on diffusion-weighted (DW) images (Fig. 1).